Additional Staging Resources

As part of the 8th Edition Project, authors were asked to develop content regarding three topics in cancer staging:

• Emerging Prognostic Factors for Clinical Care
• Risk Assessment Models
• Recommendations for Clinical Trial Stratification

Because of the rapidly evolving nature of these topics, American Joint Committee on Cancer (AJCC) did not want to limit this information to the print manual where it would remain static for the life of the edition. These topics are provided here, with the plan to update this information on a regular basis as the literature evolves. Some of this information is incomplete, but it serves as a starting point for further study.

We are pleased to offer you in this website the following prediction tools for predicting the clinical outcome of an individual patient with localized or regional cutaneous melanoma. The prediction tools can be used to predict the 1, 2, 5 and 10-year survival rates from initial diagnosis (with a 95% confidence interval) for an individual patient based on his/her relevant clinical and pathologic information. The predictive models were developed and validated using a combined database (n=28,047) from 11 major institutions and study groups participating in the development of the 7th edition of the AJCC Melanoma Staging System. This database includes 25,734 patients with localized melanoma and 2,313 patients with regional melanoma with relevant information available for model development. For detailed results regarding our prognostic factor analyses, model development and validation, please see the relevant manuscripts listed in the References section. Several additional useful prediction tools currently under development will be added to this website in the near future.